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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7736d3d5904e9f730be0e5565a97b79c74be6c95c1c6cd012e61f6070401cc20' 
  AND token = 'KyhW3anXssm08P9EWl6CFyCt4igW3kNEIYjV8TIsrZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}