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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccccda2ba885037b97d39686d0dd02213008dec7f6dd9aa1c5b5e7905722d848' 
  AND token = '0pwE4J9M4HLNhc3+zTDLDjxQihe250NlZ7UDLX6xc74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}