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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ccebb94ade8ba31c3f27486c4f003562ee81588132d9104cc4d349a92a01032' 
  AND token = 'lf0r/I8AN+yIlPRKvo/atYvTPu96kcTh8uyDKfHo1OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}