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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55720849815ba310ed674a87f6dff1e87940408271aa3bddf30fa3b1ee6e80e6' 
  AND token = 'TGp9DyLq4GRLq3WYAmfEgu+IQWolJAeWerqK1RlEsAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}