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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290d0e87b6f5e4ed258587c9d276f665d5e36124d1a86b4be03ce80d1a1c5232' 
  AND token = 'QwVHCCei7DyQbccQHZmiFknSdlLSIITf0OH9VCYiO40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}