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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0e292c6c3b793759c28b1277aa0cabd3d24fb5a27319e21ea361d361b81e07' 
  AND token = '5Gliz+PakK8r4Apq04yPkKub4tGmmPBiAExtQi8hxrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}