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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7144dcf4fce1064e5e1252986f2cfd9e9b085cd2c985826bf8205327b6335b92' 
  AND token = 'UPoudz0zJPBg00OpocL+HnvHM5fLBg7b1SJlqRehuUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}