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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1a6f161b3c7493e10edf207a95a2fd7aa474887b07ec15fbf597ee9cbfbda4' 
  AND token = 'F800AA8m0sbwSCu9DZ0HPkmcd3mJuzkQ+JH9vCmbtok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}