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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f6d44ea4c43764378e577eec2209b8f06dcc6e0bd2dd30a4c570c6bafc822e' 
  AND token = 'KCbqynW8spv4zPZIfvXtYF3yDACBzV52zKPN8bct7y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}