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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1476ce8a411e9a7ac82dc215003bfa5dc801bde295de706a05f6aae9555fe1d' 
  AND token = 'vjRiYUh3CTfFoCqttLmrgsqw3sMmZUgec5Fh34JJ1kA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}