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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7b0bf270fdf5bc2563c8291d942daaeaf5f2df2364acbf843aa83156f2ff52' 
  AND token = 'STc1RnjwNYnO6J98eLya90luKbpklMzzeafXUzXF8CU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}