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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f876b4d45a8671c1654fd33ae3fe1b5c717e7370043a4394da62e73f428d80f' 
  AND token = 'E9jToe3IltigdVjfCJIB/oRsrAq/DafnPTqVJny68Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}