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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5359167a46a3bed8403d7d2c85f51ba8d31321735acc977f55c1234db2111e4' 
  AND token = 'MIhx9CdibJzBdwjQXRTCtzcaVeN0G1SiUA3po8c1M0c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}