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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9512a7f7e50d42647b3c210e43b181f41bd273963c4173b26c3947cc284e6015' 
  AND token = '6VQCAC4sGiHkw03jVvpBFdT3wvADDskAuAkD3ZNfYis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}