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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2d38c5f1f966ce703fc5e891c9b0e3803faadf8d110571f8767a73e44990de' 
  AND token = '0C0Pw1245PhAKczS1wF8PQbyk20Qc4JeIFBkcRZYkgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}