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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63e9d06f12ebfc5cc3ad7ce10f4be5ae3be51387f9cb642f14f3c06d2e1a8996' 
  AND token = '9T1YsIrTw0Qwi2P+mNfEz6qpQ/+96kn7LGHWg3rVAkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}