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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d510a4b0e843a858dd8efdc75b1ad873f1c4f8671957a8e7b7f599c26defe6' 
  AND token = 'mwmnqhE0JIVauFOLxTOeRQOVjfh6zJT4or8DdW8d4Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}