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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42c8db5bf31d11e2a864ef25e8888492c10409dcc0b9dc334090aca9b2dbd921' 
  AND token = 'afu02OvdtLZV4hvgyewo6utYw7pJxtcLcvzHitWZoVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}