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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d5a51151b3892b35433106c590714cfe2c2c7e919749d61c862af1928276c24' 
  AND token = 'qlNJIoXgGbsNJHW+5FY14p80I9NxKL+lTEk3qkH0rVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}