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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b8533d729111e418032ad6702cdc0cc2892e5237048de18050e7121bdae701e' 
  AND token = 'BN8E6k0CNjMcVlE7MAZ7Hw+PVvwUGoVqK9qghgF2zZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}