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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd6b80a3335c1491052d46ab84c5af821d8fa0b68a8e9d3c331fb5848fdc74b0' 
  AND token = 'zYVR1gxRcvpqzkRHgJXIyeQdO0mCVUv1XBy4UDCFXuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}