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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be50220c2173d7e92cafc930e789dd773cfa7e3f8bade3bffc0af8125ae1b816' 
  AND token = '0135TicaC8NA7pLX8AamermMt0TdsHwJcs5I0TRky2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}