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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd09885a8d80fa7211979fc9726839f4eae72103157de634720226dcb0b28dfaa' 
  AND token = 'SDI4djaE9G/FfAAjDBvMCB/CoFCWJEgegTFBSrjWs/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}