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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43f58a834425bbdeff3ee11da26e89f4add5e00756b6a2a6d4551d7c69255b5' 
  AND token = 'ZhJ4s53ZpShqBTXi66D0+2eNEw/1EVjcZVYWX8pCBZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}