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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601367f6a90e482a0009f08bfdb7d085c0ce2c597b909f6c2dd13656f93a12e2' 
  AND token = 'FWIfueLBggf4ReOoUy2O6m80MbT+krw7eX7lTUhad0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}