SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cb8eecbc0f6114a118be51ba72aa8bc67e854a3f048af1c4b1806428fd9ed50' 
  AND token = 'RNUSyXCL1CEKrWstZ5ZF1hTg1IUHMYPL10xrtpvZvvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}