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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a5486b2f0a66386cd181833f500200435079c3b14a1e27482adec017185561e' 
  AND token = 'Auh18/xmy6fNo2LYAlCdU0ZG3stwIelcvmgAcuGpsgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}