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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '959278c5288da626bb0c4a04479e949d9981d3fde6f8bd9dea1f90926b638e6b' 
  AND token = 's1f6L9ZqHqpQkQDSBMMQh+cslUcsxrpo/5JTq7hA0lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}