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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40f24d3cc066f6a2d3a871a48762fe1d9a3f40cce895c444476700c0c8bc325a' 
  AND token = 'htD42heO/vbgX33xKzXlrbqRHdx5eF+zBzep0yA9SaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}