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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a52d1ee2c4f3eff8c64651035ec9adee5d86e9815b42e4f1e63b8c365b8125f5' 
  AND token = 'rYpZIgHbJUYIn9KhPPQ2gpZ3m668d4sumHrDwude3ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}