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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4c18910793b3c959743b3d1b1bf3d7018881e7959475d79a33d72a2324121b' 
  AND token = '//yWW1cs+zcUPi79Qy3xy1M2KsThO3dvibKijLIOBzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}