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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36f1d10e9c8c21a0a0d29590adce63435365e255e5105fb7188a820b007e2da3' 
  AND token = 'OL9aRdFgzCTZP8Pv6XfqxaIhG7Gc1JMrWQs4zU2b5Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}