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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24ab8ce04cd577505e0e4b01ade4dd0b17289ffeb7742c7a049c1b9cda460609' 
  AND token = 'O4sIDZg8R9dNJRAROC/AR7bMTMNQyjh8FPF5RhnuE+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}