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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a827ef6d252b52dee6cd6566ec0699b6602eb26f30d9a5a4abba629e8d20927' 
  AND token = '/DPdTEp4aDSR9DEJkvPxIwXn7iLbyrVwIA6/6UyUdA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}