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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '654bcc4e199e77a045f51e23c89442a8d876b8593dcd2122452cb0569398cef7' 
  AND token = 'oPOLWXiUXpaRAZ9IGAQDNszx7/MbUnXZa8ZKWPY0eS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}