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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '487875f368403890adf2e4e2fb3c7a62c2c946b96486a77f53adac0e0d13ff26' 
  AND token = 'fgqo6oCSAnTeDwKUklj58HPOo3c7/gAgI6oQ5MtFaS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}