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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd6460fac08277797cf98f9227f9f30d81c4f6044ebc590367692373eac549f4' 
  AND token = 'nwGSipt3CDMC71m06NiK6hXd0HGdkfOMD5OlqiDGPgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}