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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78c8cdb471547f0602661051db64318f35e876fe4a6e3f3a98e0ebb72565be89' 
  AND token = 'HvTY/NxYS59I8nUIq0o6CLhbDor0xHfpzJELPiIVf2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}