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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aab9a4f636878f595eade01089fa375592b7e9ae9d89e18736c213b674355821' 
  AND token = 'GmuySvVnhhIeNYQ3Q84h0VV8wVqxc5WoG/1WN3Zs3kY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}