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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c0c4c91e1fee6600f8834b448101e314c1f803630561a4de650f5c680f7f018' 
  AND token = 'bpJ5wrAQ9Am0ehWUqS/6wzVT4PBF/4yqJR/3ex+VImM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}