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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8aec2420f2b7aa205ea8af36b8513befc7260c9ed83191a4ba2c71d487224e35' 
  AND token = '44gidwLKu9KR/XgXn1k+dnrf5au89b8dvVhb8oAed8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}