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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9f648aeadaf625a0c2698c8e7732b14243b374cf683e656760af8a8e2f00fc0' 
  AND token = 'PAcACeKeTk4JGWjUdbVnOdc9ATnb9tQV/PJMM09wRZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}