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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e6d3b0bcfc6a90fbb68f71ea620e5cf5563138add21e7ec7a1fd9a06984341' 
  AND token = 'Jkr+INEyghWbxFqB3Oh4oEJimpgDIB/63tA9NDtHsw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}