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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375fa794f2cac91eaf7e4c5ca22a8a14d82e78802630f576977716c19696033f' 
  AND token = 'laKAbRtZ7bQ9+tWee+xdb9vlhtiwN+8YokwQQ54a0i4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}