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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8519902559eb9d7a5310f67d619ccfa2b4731232016b33718c7bcc4a173fffb' 
  AND token = '+1wsJd9WBD0TCUN3EKHxwfLBbDIB7N9JCydhVOsJkq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}