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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3408575f8378503acae1f1a37a2598866a1638e25c196cef240a98b82fd21fc7' 
  AND token = 'EM/41/x0I1Xjizy2K8VgXoiLrqFvnEtKpVA7Sj7gGcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}