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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efa461f93b989331ef9d27e6d6d8274ad275db54266050a675b15072807c5395' 
  AND token = '8D0uzHBg5FgLTFpctkTRaTtCI0Q7UxTTKZoLdPI4c1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}