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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe152d4f6a058bfda2f0d352a456165eedf13919b26b60a844062d8663d5efa' 
  AND token = 'cD2u//8oB7SlQcefQ/1wfxuojL29ffMD0oIjo64wqzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}