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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23750801f3f46dfdfd99ce8bd6429a45cb5b927c2140caa28139e431721f98cb' 
  AND token = 'wGYxx5DFJv13Ic5PaVUVja02s+I6zTe2iuwEAnnnrhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}