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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '754ca7ace3752b659432f91bb9b817553db7a94b1bcbca8893ae6731746666dd' 
  AND token = 'c5XHT4V3X5pac5AriDaul1v26D2T5iU8xKig9MSOuQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}